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Journal Articles Nutrients Year : 2017

Vitamin D and Age-Related Macular Degeneration.

Alfredo Garcia Layana
  • Function : Author
Angelo Maria Minnella
  • Function : Author
Gerhard Garhöfer
  • Function : Author
Tariq Aslam
  • Function : Author
  • PersonId : 1020987
Anita Leys
  • Function : Author
  • PersonId : 1020988
Cécile Delcourt
Johanna M Seddon
  • Function : Author


In recent years, the relationship between vitamin D and health has received growing attention from the scientific and medical communities. Vitamin D deficiencies have been repeatedly associated with various acute and chronic diseases, including age-related macular degeneration (AMD). Its active metabolite, 1α,25-dihydoxy vitamin D, acts as a modulator of cell proliferation, differentiation and apoptosis, and cumulative data from experimental and observational studies suggest that relatively a lower vitamin D status could be a potential risk factor for the development of early and/or late AMD. Herein, we made a narrative review of the mechanisms linking a potential role of vitamin D with the current concepts of AMD pathophysiology.
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Dates and versions

hal-01617177 , version 1 (19-10-2017)



Alfredo Garcia Layana, Angelo Maria Minnella, Gerhard Garhöfer, Tariq Aslam, Frank G. Holz, et al.. Vitamin D and Age-Related Macular Degeneration.. Nutrients, 2017, 9 (10), pp.1120. ⟨10.3390/nu9101120⟩. ⟨hal-01617177⟩


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